Strefa zawodnika

Metody i środki dopingowe

Artykuły zawarte w tym dziale nie mają charakteru instruktażowego. Autor witryny informuje ze zażywanie środków farmakologicznych powoduje trwały uszczerbek na zdrowiu a nawet prowadzi do śmierci
 
1. Czym są sterydy ?
2. Nolvadex vs. Clomid for PCT
3. Doping pod państwowym nadzorem
4. Pozytywne skutki używania sterydów w medycynie
5. Jak działają sterydy?
6. Anadrol vs. Dianabol

Powrót do strony głównej


Anadrol vs. Dianabol

For many years, a great debate has raged over which oral is superior for mass gains, and two of them have stood the test of time; dianabol and anadrol. The debate has continued, arguing which of the two is superior, yet no conclusive evidence has proven one better than the other. People respond to each one differently, some swearing by dbol and some swearing by anadrol. Before we declare one the winner, I am going to go over a bit of history and chemical structure on both products.

Anadrol (oxymetholone) was first made available in the 1960’s by Syntex. It is very effective at increasing red blood cell production and was promising for treating severe cases of anemia. With the advent of newer and more advanced drugs such as Erythropoietin, which have less androgenic side effects, Anadrol was discontinued. New studies in AIDS/HIV patients revealed Anadrol was particularly effective at reducing wasting symptoms so it was re-released in the late 1990’s.

Oxymetholone is a derivative of dihydrotestosterone, which in theory means it should not convert to estrogen. Since it does not aromatize but still causes gynecomastia in some users, there are other pathways by which it converts. After looking at studies on AIDS patients, I found that it may convert by actively activating the estrogen receptor, so this is a product that would need an anti-estrogen such as Nolvadex.

Dianabol (methandrostenolone) was first made in 1956 by John Zieglar of Ciba fame. Dianabol has been one of the most popular oral steroids of all time, exploding in popularity in the 1970’s with bodybuilders and football players and expanding into all avenues of athletics during the 1980’s. It somewhat waned during the 1990’s with the steroid control act, but was hot again in the early 2000’s with reproduction in mass quantities by Mexican labs and underground labs.
Methandrostenolone is a derivative of testosterone and hence will convert to estrogen. Gyno will be a concern for sure, in almost all users, whereas only less than 25% have problems with Anadrol. Again water retention will be a problem, usually due to the estrogenic properties.

Both products will have similar androgenic side effects, which include; acne, water retention, oily skin, male pattern baldness, and increased body hair growth. Both drugs are c17 alpha alkylated, therefore liver protection will be necessary, especially when combining the two.

So we come to the premise of this article, Anadrol vs. Dianabol. Why, the great debate over which product to take? They work on different pathways, have similar side effects you will have to combat, and both are liver toxic. So why is there a debate over which is better and which one should you take? Well, as I stated earlier, different people have different responses to each product. Many people, including myself, find high doses of Anadrol to be too much to handle in trade of the results you get. With this product, I have an extreme loss of appetite, massive water retention, and overall aches and pains and headaches.

On the other hand, when I take Dianabol, I get a general sense of well-being, good but not great size gains, and the ability to keep eating. It sounds like I should keep taking Dianabol and drop the Anadrol, right? Wrong. I get massive male pattern baldness from Dianabol, which I do not experience from Anadrol. I have an increase in blood pressure levels at doses that are high enough to match my gains from Anadrol, and I have to shorten my cycles because of the massive dosages I take to get good gains. So in all, I get some side effects from each that I would like to avoid, while still retaining the great benefits that I can only get from each product.

Anadrol is well known for its ability to cause massive size and strength increases, and as we all know, a stronger muscle has to become a bigger muscle with enough calories to feed it. Dianabol gives me large, quality muscle gains without as much water retention as Anadrol. So what is the compromise? Do I take one during one cycle and then the other product during my next cycle?

The answer is no to both. There is no need to short change yourself gains in either department when you can have your cake and eat it too. I am not alone in my assessments of both products. Most guys have similar issues of massive water retention, headaches and loss of appetite with Anadrol, and MPB and fewer gains with Dianabol comparatively. So, the best thing we can do is decrease our dosages of both products to cut down on side-effects and take them at the same time to increase the benefits.

My recommendation is to take both products in lower dosages but for longer periods of time. Dianabol has been found to work much better for quality gains when taken in lower dosages but for longer periods of time. High doses have severe side effects in some users, a loss of all gains with cessation of the product because of the short cycle (4-6 weeks) and most of the aforementioned side-effects.

Your dosages will be cycle history dependent but when I was at the peak of my career, I was taking cycles of 200mg Dianabol for 6 weeks per cycle, or 250-300mg Anadrol per 6 week cycle. In later cycles when I decided to combine the two products together, I was able to drop my Dianabol use to 50mg per day, and my Anadrol use to 100mg per day and because of the synergistic effect of the two products combined, the effect was similar to high doses of each but with none of the sides. There is something very synergistic when taking these two products together with just a simple cycle of testosterone and deca-durabolin.

I would run my Anadrol cycles for 8 weeks at that dose and my Dianabol cycles for 10 weeks at that low dose with no liver toxic effects as proven by my quarterly blood tests. I did not have to take liver protectants, but I recommend them for most users. I no longer had to watch my blood pressure, my water retention was minimal compared to earlier cycles, and I was able to continue eating massive amounts of food because I did not experience appetite loss from a massive dose of Anadrol.

I highly recommend on your next bulking cycle you try the following: A base cycle of test and deca, add in the Anadrol and Dianabol mix, and some Nolvadex. You will be able to control your water retention, liver toxicity, and other side effects by controlling your dosages. Your doses will vary from mine, but just adjust accordingly and run them for longer periods of time. You will be amazed at the simplicity of this cycle and yet the synergy is un-describable. Your gains will be far better than you have ever had when taking each product alone, your side effects will be less than if you were to take either product in higher doses, thanks to the different biochemical pathways. Everyone already knows that test and anadrol, and deca and dbol are very synergistic. Now combine all four in a cycle and watch yourself just blow up.

 

Do góry


Jak działają sterydy?

Before we get into how steroids work, let's define Anabolic steroids. The word anabolic simply means building up as opposed to catabolic that means breaking down. Anabolic steroids are manufactured or synthesized derivatives of the male hormone, testosterone. Testosterone has two main functions on the body, the anabolic effect and the androgenic effect.

1. The anabolic effect is responsible for growth, muscular development, and the masculine body contour of the adult male.

2. The androgenic effect stimulates the development of the male secondary characteristics after puberty, causing growth of the beard, pubic hair, development of the penis, and change of voice.

In order to understand how steroids work, you first need a brief lesson in pharmacology. Pharmacology is the study of drugs in your body. It is important for you to know exactly what happens when a drug enters your system to understand the effects that drugs have on your body, more specifically, the effects of anabolic steroids.

There are basically two types of effects drugs have on your body, therapeutic effects and nontherapeutic effects. Therapeutic effects are the intended effects of a drug. Nontherapeutic effects are simply the side effects or the adverse effects. In the case of steroids, the therapeutic effect would be to increase muscle size. The side effects are all the undesirable things that can occur. We will get into all the potential side effects of steroids later. For now, I want to educate you on how they work.

All drugs have their own way of working, or what is called, a mechanism of action. Most drugs' mechanisms of action involve drug receptors. Drug receptors are located on cells in your body. To understand this concept, all you need to do is first picture one of your cells and then picture an outlet, like the one on your wall. Now picture several of these outlets, better known as receptor sites, on the cells. These receptor sites or outlets located on or in your cells either trigger or block biological activity when stimulated or occupied. Drugs occupy, bind or plug into the outlets to either stimulate or block biological activity.

Biological activity means all the biochemical and physiological activities that normally occur in the body such as your heart rate. It is important to note that drugs do not create effects of their own, they change the biological processes already occurring in the body. For example, you have always had a heart rate, hopefully. Some drugs can change your heart rate by either speeding it up or slowing down.

Anabolic steroids work by stimulating the anabolic effect discussed earlier by binding or plugging into protein receptors in or on the cells that help create new proteins in the cells. This increased biological activity is called an increase in Ribonucleic Acid Activity (RNA Activity). The construction of new proteins helps increase muscle size and strength. Remember, this normally happens in the body. The steroids stimulate or increase this biological process by binding to the receptor sites on the protein cells.

Just to give you an idea of how other drugs work similarly: Aspirin works or relieves pain by binding to receptors on cells that are responsible for transmitting pain and inflammation. By binding on the pain receptors, aspirin blocks pain and inflammation. On the other hand, aspirin causes stomach upset by also blocking the production of a protective enzyme in the stomach.

A betablocker is a type of blood pressure medication that works by binding to beta receptors on your heart cells that have a direct effect on blood pressure. By binding to the beta receptors on the cells, they prevent the heart from working harder, which helps decrease blood pressure. On the other hand, betablockers sometimes cause fatigue and even impotence by blocking or stimulating other biological activities.

So remember, there is always a tradeoff!

Steroids are also known to increase nitrogen retention, another biological activity. Nitrogen is found in proteins where it plays an important role in the building of tissues. Those who use steroids have been known to have a positive nitrogen balance, a preferred state where intake of nitrogen from proteins is greater than excretion of nitrogen.

Once a drug enters the body, the body begins to process the drug that includes four processes:

1. absorption
2. distribution
3. metabolism
4. excretion

Absorption
Drugs are usually administered either orally or intravenously.
When drugs are administered orally, absorption is much more complex than when administered intravenously. The drug has to bypass a number of barriers before it can get into the blood stream and do its thing. First, it must get past the acid in the stomach. Second, it must over come bacteria in the small intestines. Third, it must survive changes in the small intestines. Finally, it must survive the metabolism process in the liver known as the first pass effect.

During the first pass effect, blood travels to the liver as part of a filtering system where enzymes in the liver metabolize or change part of a drug before it enters the bloodstream. Enzymes are proteins that change drugs in the body and also help biochemical reactions occur as discussed above.

Drugs are absorbed faster when administered intravenously. They enter the blood stream immediately, and aren't absorbed like when taken orally. They bypass being metabolized by the liver, skipping the first pass effect.

Distribution
The distribution process simply involves the transportation of drug throughout the blood stream.

Metabolism
Metabolism is the chemical change a drug goes through in the body. The major place where this takes place is in the liver.

Excretion
Excretion is simply the removal of drug from the body. The kidneys are responsible for most drug excretion through the urine. Some drugs such as steroids are excreted by the liver. Drugs are also excreted through the breast, skin and lungs.

 

Do góry


Pozytywne skutki używania sterydów w medycynie

Sports orthopaedics expert Kevin Plancher, M.D., on positive uses for steroids in medicine: Despite a flurry of information on steroids, too few of us actually understand what steroids are, what they can do to the body - and what they can do for it. 

"The news on steroids is not all bad," explains Kevin Plancher, M.D., a leading NY-area orthopaedist, sports medicine expert and official orthopaedic surgeon of the U.S. Ski and Snowboard teams. "In fact, some of the news is quite good." Much of the current confusion over these drugs stems from the fact that the term "steroid" is used to describe numerous synthetic drugs that affect hormone levels in the body. "Of course, that means that steroids are used every day to effectively - and legally - treat a host of medical conditions," Dr. Plancher says. "The key is in differentiating these drugs from the ones that are apt to do more harm than good," he adds. 

The "Good" Steroids 

Corticosteroids differ chemically from the anabolic- androgenic steroids that are the talk of the sports media today. "Corticosteroids are vital to the practice of medicine," Dr. Plancher notes. "Because they exhibit potent anti-inflammatory effects, they are used most commonly to treat arthritis, as well as short-term inflammation associated with orthopedic injuries," he adds. "Corticosteroids are also widely used to treat asthma, in both inhalant and oral applications." In addition, they are popular active ingredients in topical creams used to treat rashes and other skin disorders. 

Even the "Bad" Steroids have a good side 

Anabolic Androgenic Steroids replicate male hormones in the body, and are among those drugs used illegally by athletes and bodybuilders to enhance their performance. Yet, even this class of drugs has a potentially beneficial medical use. "Anabolic steroids have a very limited scope of legal use here in the United States," Dr. Plancher says. "But they can be helpful in a number of critical situations, and there is research underway to study their effects in still other problematic areas where current protocols are not yielding optimal results." 

For example, some patients suffering with long-term, serious illnesses can develop Chronic Wasting Disease, marked by drastic weight loss and an inability to gain it back - no matter how much they eat. "Anecdotally, we hear of patients who take Anabolic Androgenic Steroids to regain lean muscle after being diagnosed with Chronic Wasting Disease, and the evidence is positive," Dr. Plancher notes. Similarly, pilot studies have been exploring the effectiveness of this class of steroids to assist in the rehabilitation of patients with COPD, and to address certain problems that can lead to infertility. 

"We want to avoid the common misperception that all steroids are alike," Dr. Plancher explains. "But at the same time, we also must stress that any time a patient is taking any kind of steroid, he or she should be closely monitored by a physician," he adds. That's because many of the same problems associated with Anabolic Androgenic Steroid abuse can also occur with other steroids. "Doctors whose patients are taking steroids, whether for arthritis, asthma, rehabilitation, or as an experimental treatment for a serious medical condition, should be watchful for a number of serious potential side effects," he says. They include liver and kidney malfunction, cardiovascular problems due to increased levels of LDL ("bad" cholesterol), hypertension, and stunted growth in adolescents. Other potential risks are cosmetic, such as the development of severe acne, and psychological, such as depression or rage. 

"Yet, all of these symptoms are far less likely to occur if a doctor is managing the quality, duration and dosage of the steroid therapy," Dr. Plancher assures. "The key to successfully using these or any other drugs is to use the smallest dose of the best medication available to treat the exact duration of any given medical condition."

Do góry

 

Doping pod państwowym nadzorem

Trzeba było czekać 20 lat, by wyciągnąć na światło dzienne wstydliwy sekret wschodnich Niemiec - oszustwa w sporcie. Werner i Brigitte Franke przylecieli do Berlina w grudniu 1990r oku. Z lotniska pojechali 70 kilometrów na południowy wschód. Byli w kraju, ledwie parę miesięcy przedtem nazywał się Niemiecka Republika Demokratyczna. Zatrzymali się w uzdrowisku Bad Saarow. Wysoki płot skrywał cel ich podróży: Wojskową Akademię Medyczną. Dotarli do miejsca, w którym ukryto Państwowy Program Badawczy 14.25 - wstydliwy sekret wschodnich Niemiec.

Po upadku muru berlińskiego w 1989 roku z Niemiec zachodnich przysyłano wielu specjalistów, którzy mieli poznać socjalistyczny przemysł, administrację, instytucje publiczne i przedstawić plan zjednoczenia państwa. Akademia Nauk poprosiła doktora Wernera Franke, światowej sławy biologa molekularnego, o ocenę niektórych wschodnich placówek naukowych.
Wernera Franke zaintrygowało odkrycie, że kilka prac doktorskich na tematy sportowe i medyczne powstało w Bad Saarow. W tym miasteczku nie było uniwersytetu, jedynie Wojskowa Akademia Medyczna.

Franke czuł, że coś tu śmierdzi. Kraj mający ledwie 17 milionów ludzi zgromadził tyle lekkoatletycznych rekordów, że dorównywał, a czasem przewyższał takie giganty światowego sportu, jak USA i Związek Radziecki. Jak oni to robili? Franke i inni eksperci byli przekonani, że to władze państwa organizowały i finansowały dostarczanie zawodnikom środków dopingujących, które przerabiały ich w pogromców stadionów. Franke w młodości był trenerem obiecującej dyskobolki Brigitte Berendonk. Wychowała się ona we wschodnich Niemczech, lecz uciekła na Zachód. Zrobiła takie postępy, że zakwalifikowała się na olimpiadę w Meksyku. Spotkała tam koleżankę z NRD Margittę Gummel. Margitta nie przypominała nastolatki, którą pamiętała Brigitte. Była umięśnioną olbrzymką - pchała kulą na odległość prawie 20 metrów.

W wiosce olimpijskiej mówiło się o tabletkach, które zwiększają masę ciała i siłę. Było tajemnicą poliszynela, że niektórzy zawodnicy brali je, by poprawić wyniki. Po powrocie do kraju Brigitte napisała artykuł o swych podejrzeniach. Tekst przeszedł bez echa. Werner i Brigitte zrezygnowali ze sportu. Werner zdobył sławę w dziedzinie medycyny. Brigitte została nauczycielką.
Pobrali się w 1975 roku, wychowali dwoje dzieci - i nie tracili nadziei, że prawda o specyfikach zwiększających osiągnięcia sportowe wyjdzie na jaw.

W Bad Saarow Franke spotkał się z uprzejmym przyjęciem; to od jego oceny zależało utrzymanie pracy lub jej utrata, awans lub dymisja. Oglądał aparaturę i rozmawiał z ludźmi. Potem poprosił o listę prac doktorskich. Ich tematy nie miały nic wspólnego ze sportem. Bibliotekarz szepnął, że takie prace są w budynku komendantury.
- Może pan poznać tytuły i nic więcej - oświadczył komendant.
Katalog ujawnił około 30 dysertacji z napisem ?ściśle tajne". Osiem dotyczyło sportu. Pierwsza nosiła tytuł: Wpływ sterydów anabolicznych na poprawienie wyników skoków w lekkiej atletyce. Autorem był Hartmut Riedel, naczelny lekarz ekipy lekkoatletycznej NRD.

Werner był przejęty swym znaleziskiem, ale wiedział,że jeżeli okaże podniecenie, to te dokumenty mogą zniknąć na zawsze.
- Dziękuję panom, to na razie wszystko pożegnał się i wrócił do Heidelbergu.
Zdobył dokument upoważniający go do ?sprawdzenia wszystkich prac, również tych, które są opatrzone klauzulą ?ściśle tajne?. W razie potrzebymoże je wypożyczyć celem dokładniejszego sprawdzenia". Następnego dnia Werner Franke z żoną leciał do Berlina.
W Bad Saarow najpierw spotkał się z podoficerem łącznikowym Bundeswehry.
- Ma pan pieczątkę z napisem ?odtajnione"? - zapytał go Werner.
- Tak jest.
Dowódca kompanii ochrony oraz dwaj wojskowi lekarze już na nich czekali.
Po długich targach i sprawdzaniu upoważnienia przyniesiono 8 opasłych tomów. U góry każdej strony widniał czarny stempel: ?Uertrauliche Verschlul3sache" (ściśle tajne).
Ponad godzinę robili notatki, ale prace były za długie, a nazwiska częściowo zaszyfrowane.
- Materiał jest za duży, by ocenić go na miejscu - oświadczył Franke
i z żoną zaczęli wkładać prace do torby. Jeden z żandarmów wyskoczył z pokoju.
Po chwili do środka wpadł dowódca kompanii ochrony.
- Te dokumenty wyniesiecie po moim trupie! - ryknął.
Po długich targach zgodził się podporządkować rozkazom najwyższego rangą oficera służb medycznych w okolicy, majora Bundeswehry. Ale Werner wiedział, że stąpa po niepewnym gruncie. Tym razem przyjechał do akademii z własnej inicjatywy. Za przelot i samochód zapłacił z własnej kieszeni. Akademia Nauk nie upoważniła go do szukania takich dokumentów.
Gdy przybył major Bundeswehry, Franke zaprosił do pokoju także podoficera łącznikowego. Pospiesznie kartkował rozprawy.

Wyrzucał z siebie potok terminów naukowych, zwracał uwagę na pogwałcenie etyki oraz prowadzenie eksperymentów na nieletnich. Major kiwał głową, a Werner szybko podsuwał prace podoficerowi łącznikowemu, który natychmiast stemplował okładkę - ?odtajnione". Ta czarna pieczątka miała moc urzędową. Franke wygrał.
Werner zajął się rozszyfrowaniem nazwisk z dokumentów, a Brigitte zmieniała rękopis książki o dopingu, włączała nowe sensacyjne materiały. Książka ukazała się we wrześniu 1991 roku.

Ale całą przerażającą prawdę świat poznał dopiero w 1997 roku. Wtedy to państwo Franke podsumowali swe 6-letnie badania i analizy. Ujawnili, że kilka placówek naukowych i sportowych, a także setki lekarzy i trenerów systematycznie wykorzystywało mężczyzn, kobiety i dzieci jako laboratoryjne myszy w programie badawczym dopingu, nazwanym Państwowym Programem Badawczym 14.25. Obejmował on tysiące zawodników. Werner znalazł dowody, że doping stosowano już w połowie lat 60. Wtedy trenerzy i lekarze eksperymentowali ze sterydami i ze środkami pobudzającymi, jak amfetamina. W 1966 roku wybranym zawodnikom podawano turinabol, steryd anaboliczny, który produkowała państwowa firma Jenapharm.

W 1968 roku podjęto tragiczną w skutkach decyzję, by podawać kobietom męskie hormony. Jedną z pierwszych była Margitta Gummel uprawiająca pchnięcie kulą. Już po 11 tygodniach brania turinabolu pchała kulą 2 metry dalej. Podejrzenia Brigitte były więc uzasadnione.

Wyniki olimpiady w 1968 roku były tak satysfakcjonujące, że postanowiono podawać turinabol praktycznie wszystkim ekipom. Scentralizowano więc dystrybucję środków dopingujących. Zajmowała się tym tajna komórka w Sportowej Służbie Medycznej. Całość kontrolowała tajna policja - Stasi. Obecnie sterydy anaboliczne stosuje się we wszystkich dyscyplinach olimpiskich z wyjątkiem żeglarstwa i gimnastyki kobiet. Z dotychczasowych doświadczeń wynika, że dla zawodniczek najbardziej korzystna jest kuracja hormonami anabolicznymi - w 1977 roku pisał do Stasi doktor Manfred Hóppner ze Sportowej Służby Medycznej. Hoppner i jego koledzy po fachu doskonale zdawali sobie sprawę, jakie szkody wyrządzają w organizmie dorastającej dziewczyny męskie hormony - rozregulowują jej system endokrynologiczny. Jednak faszerowano nimi nawet drobniutkie gimnastyczki.
Tysiące enerdowskich 13-, 14-letnich dziewczynek łykało dwa razy więcej męskich hormonów niż ich koledzy z boiska.
- To witaminy - mówili trenerzy.
Wielu podawano czysty testosteron, naturalny hormon wpływający na popęd seksualny, agresję oraz takie męskie cechy, jak rozwinięte muskuły, owłosienie na ciele, niski głos. Dziewczęta widziały, co się dzieje z ich ciałem, rozmawiały ze sobą o owłosionych nogach czy grubszym głosie i wysypce. Jednak tym, które protestowały bądź chciały odejść z drużyny, grożono i oskarżano o brak patriotyzmu.

Lista substancji, które podawano enerdowskim sportowcom liczy 25 pozycji. Z tysięcy sportowców objętych ?programem 14.25" tylko dwu złapano na braniu sterydów. Tak fachowo przygotowywało oszustwa ZDKL - laboratorium, które miało licencję Międzynarodowego Komitetu Olimpijskiego. Wszędzie na świecie laboratoria MKOl miały wykrywać doping, lecz w NRD cel był dokładnie przeciwny: laboratorium w Kreischa miało zagwarantować, że sportowcy na kontroli antydopingowej okażą się ?czyści". Największe dawki sterydów podawano w NRD ciężarowcom. Mężczyznom zaczęły rosnąć kobiece piersi. Kilkunastu ciężarowców musiało te niechciane piersi usunąć chirurgicznie. Dziewczęta miały tak widoczne skutki uboczne, jak owłosienie całego ciała i zarost na twarzy. Ponadto cierpiały na szereg poważnych dolegliwości: zahamowanie wzrostu, bezpłodność, rak wątroby, zatrzymanie miesiączkowania i poważne schorzenia ginekologiczne.

Nawet Hóppner skarżył się Stasi, że niektórzy trenerzy wstrzykują testosteron w zbyt dużych ilościach. Doświadczyła tego na sobie Heidi Krieger, mistrzyni Europy z 1986 roku w pchnięciu kulą. Kilka lat temu poddała się operacji zmiany płci i teraz jako Andreas Krieger pracuje w sklepie zoologicznym w Berlinie.
Z książki Wernera i Brigitte Franke wynika przerażający wniosek, że praktycznie wszystkie złote medale olimpijskie od 1968 roku sportowcy NRD zdobyli nieuczciwie.
Enerdowscy sportowcy w większości siedzieli cicho, gdy małżeństwo Franke ujawniało swe odkrycia. Jednak wystąpiło kilku odważnych, którzy opisali swe przeżycia.
- Dostawałam zastrzyki, po których byłam napastliwa, zaczepna. Na stu metrach zyskałam dwie sekundy - powiedziała pływaczka Karen Ktinig, dwukrotna mistrzyni Europy w stylu dowolnym oraz uczestniczka sztafety 4 razy 100 metrów, która na igrzyskach w 1980 roku ustanowiła nowy rekord świata.
Inna była przemiana Christiane Knacke, która w 1977 roku ustanowiła rekord świata na 100 metrów w stylu motylkowym. Zażywając męskie hormony przytyła 10 kilogramów w ciągu zaledwie 2 miesięcy i bez wysiłku pływała na treningach 20 kilometrów dziennie.
Te dwie pływaczki przeżyły. Detlef Gerstenberg - nie. Jego śmierć w 35 roku życia pośrednio spowodowało przyjmowanie sterydów. Gerstenberg był gwiazdą rzutów młotem. W 1980 roku dotarł do olimpijskich finałów. Kiedy trenował do następnych igrzysk, przez ponad 8 miesięcy brał turinabol. Jednak NRD przyłączyła się do radzieckiego bojkotu olimpiady w Los Angeles i Gerstenberg nie zdobył medalu.
W 1993 roku miał operację uszkodzonej wątroby - zmarł w wyniku komplikacji pooperacyjnych.
Ilu ludzi zapłaciło tę najwyższą cenę? Nikt nie wie. W ostatnich dniach komunizmu Stasi zniszczyła karty zdrowia wielu sportowców.

W 1991 roku Werner i Brigitte Franke wnieśli oficjalne powództwo przeciw byłym władzom sportowym NRD. Oskarżają je w imieniu sportowców o umyślne uszkodzenie ciała. Kilku lekarzy i trenerów uznano już za winnych, lecz oni celują w głównych szefów ?programu badawczego 14.25".
W kwietniu 1999 roku byłemu dyrektorowi Sportowej Służby Medycznej wymierzono najwyższą w historii Niemiec grzywnę. Udowodniono mu w 109 przypadkach współudział w uszkodzeniu ciała z powodu podawania zawodnikom środków dopingujących.

Jednak rzetelne zamknięcie sprawy zależy od samych sportowców. W czerwcu 1998 roku wystąpiło troje najdzielniejszych: Christiane Sommer (dawniej Knacke), Carola Beraktschjan (dawniej Nitschke, która w 1976 roku ustanowiła rekord na sto metrów stylem klasycznym) i Andreas Krieger. Oświadczyli, że chcą zwrócić medale, gdyż zdobyli je nieuczciwie.
Dla trójki sportowców ten symboliczny gest był - paradoksalnie największym zwycięstwem. W istocie było to zwycięstwo podwójne tryumf uczciwości nad oszustwem i tryumf jednostki nad systemem totalitarnym, który traktował człowieka jak bezmyślnego robota.

Na podstawie publikacji : Rudolfa Chełińskiego i Olivi Moussouris

 

Do góry


Nolvadex vs. Clomid for PCT

It seems like everyday questions concerning PCT pop up, and weather one should use either Clomid or nolva or a combo of both. I hope that this article written by BigCat may help to clear up some misconceptions.

While practically similar compounds in structure, few people ever really consider Clomid and nolva to be similar. Its not just a common myth in steroid circles, but even in the medical community. This misconception originates from their completely different uses. Nolvadex is most commonly used for the treatment of breast cancer in women, while Clomid is generally considered a fertility aid. In bodybuilding circles, from day one, Clomid has generally been used as post-cycle therapy and Nolvadex as an anti-estrogen.

But as I intend to demonstrate this is in essence the same. I believe the myth to have originated because nolva is clearly a more powerful anti-estrogen, and the people selling Clomid needed another angle to sell the stuff, so it was mostly used as a post-cycle aid. But few users really understand how Clomid (and also Nolvadex, logically) works to bring back natural testosterone in the body after the conclusion of a cycle of androgenic anabolic steroids. After a cycle is over, the level of androgens in the body drop drastically. The body compensates with an overproduction of estrogen to keep steroid levels up. Estrogen as well inhibits the production of natural testosterone, and in the period between the return of natural testosterone and the end of a cycle, a lot of mass is lost. So its in everybody's best interest to bring back natural test as soon as humanly possible. Clomid and Nolvadex will reduce the post-cycle estrogen, so that a steroid deficiency is constated and the hypothalamus is stimulated to regenerate natural testosterone production in the body. That's basically how the mechanism works, nothing more, nothing less.

Both compounds are structurally alike, classified as triphenylethylenes. Nolvadex is clearly the stronger component of the two as it can achieve better results in decreasing overall estrogen with 20-40 mg a day, than Clomid can in doses of 100-150 mg a day. A noteworthy difference. Triphenylethylenes are very mild estrogens that do not exert a lot, if any activity at the estrogen receptor, but are still highly attracted to it. As such they will occupy the receptor and keep it from binding estrogens. This means they do not actively work to reduce estrogen in the body like Proviron, Viratase or arimidex would (by competing for the aromatase enzyme), but that it blocks the receptor so that any estrogen in the body is basically inert, because it has no receptor to bind to.

This has advantages and disadvantages. The disadvantage is that when use is discontinued, the estrogen level is still the same and new problems will develop much sooner. The advantage is that it works much faster and has results sooner than with an aromatase blocker like Proviron or arimidex. Therefor, when problems such as gynocomastia occur during a cycle of steroids one will usually start 20 mg/day of nolva or 100 mg/day of Clomid straight away, in conjunction with some Proviron or arimidex. The proviron or arimidex will actively reduce estrogen while the Clomid or Nolvadex will solve your ongoing problem straight away. This way, when use is discontinued there is no immediate rebound.

So which one should you use? Well personally, I'd have to say Nolvadex. Both as an on-cycle anti-estrogen and a post-cycle therapy. As an anti-estrogen its simply much stronger, demonstrated by the fact that better results are obtained with 20-40 mg than with 100-150 mg of Clomid. For post-cycle, this plays a key role as well. It deactivates rebound estrogen much faster and more effective. But most importantly, Nolvadex has a direct influence on bringing back natural testosterone, where as Clomid may actually have a slight negative influence. The reason being that tamoxifen (as in Nolvadex) seems to increase the responsiveness of LH (luteinizing hormone) to GnRH (gonadtropin releasing hormone), whereas Clomid seems to decrease the responsiveness a bit1.

Another noteworthy fact about Nolvadex is that it acts more potently as an estrogen in the liver. As you remember, I mentioned that clomiphene and tamoxifen are basically weak estrogens. Well, tamoxifen is apparently still quite potent in the liver. This offers us the positive benefits of this hormone in the liver, while avoiding its negative effects elsewhere in the body. As such Nolvadex can have a very positive impact on negative cholesterol levels2 in the body, and therefore too should be considered a better choice than Clomid. It will not solve the problem of bad cholesterol levels during Steroid use, but will help to contain the problem to a larger degree.

Another reason why I promote the use of Nolvadex over Clomid post-cycle (as if being 3-4 times stronger and having more of a direct effect on restoring natural test wasn't enough) is because it's a lot safer. Not just because it improves lipid profiles, but also because it simply doesn't have the intrinsic side-effects that Clomid has. Clomid causes more acne for sure, but that's mainly because you need to use a 3-4 times higher dose. But Clomid seems to also affect the eyesight. Long-term Clomid therapy causes irreversible changes in eyesight3 in users. Irreversible. For me that alone is reason enough to prefer Nolvadex.

Lastly, one should be aware that use of these compounds can reduce the gains made on steroids. Nolvadex more so than Clomid, simply because it is stronger. Estrogen is responsible for a number of anabolic factors such as increasing growth hormone output, upgrading the androgen receptor and improving glucose utilization. This is why aromatizing steroids like testosterone are still best suited for maximum muscle gain. When reducing the estrogen levels, we therefore reduce the potential gains being made. For this reason one may opt to try Clomid during a cycle instead of Nolvadex. Although I would imagine that the problem that needed solved would be of more concern, in which case nolva remains the weapon of choice. It's a plain fact that there is a high correlation between gains and side-effects. Either you go for maximum gains and tolerate the side-effects, or you reduce the side-effects, and with it the gains. That's life, nothing is free.

Stacking and Use:

If problems of Gynocomastia or other estrogen related symptoms tend to pop up during a cycle the use of 20-30 mg of Nolvadex or 100 mg of Clomid daily should easily contain the problem, and be used until a few days after the problem subsides. For best results and the least amount of problems upon cessation it is best stacked with Proviron (50 mg) or arimidex (0.5 mg) for this duration as well. Its not advised that these products be ran concomitantly with the steroid for the entire duration of the stack, as this will reduce your gains. Instead cease the usage of anti-estrogens once the problem is contained, and should the problem resurface, simply recommence the use of the products in the same manner as described above.

Once a cycle of steroids is concluded one should always initiate a post-cycle therapy to help bring back natural testosterone as soon as possible. This will help you to retain the mass you gained. How this is done depends highly on the type of steroid used. If only orals were used, therapy should start immediately, even the last day of the stack. If short-acting esters or water-based injectables were used, therapy should commence within 4-7 days after last injection, and if long-acting esters were used then it should commence 1.5 to 2 weeks after the last injection was given. The length of the therapy will vary as well, from 3-5 weeks. The longer acting the product was, the longer therapy should be continued to make sure all suppressive factors are cleared before use of Clomid/Nolvadex is discontinued.

For best results, it is best stacked with HCG (Human Chorionic gonadotrophin), which functions as an LH analog and can help bring testicle size back up. HCG use starts the last week of a cycle, and on from there every 5-6 days (usually 1500-3000 IU) and discontinued 1.5 to weeks prior to the cessation of Nolvadex/clomid. The reason being that HCG itself is also suppressive of natural testosterone and should be out of the body before therapy is over, or it will inhibit natural testicle function. But I can not stress enough that HCG possibly plays a more important role in post-cycle therapy than clomid/Nolvadex. For Clomid and Nolvadex, doses are usually tapered down. Its best to start with 40-50 mg of Nolvadex or 150 mg of Clomid for the first week or the first two weeks, and then finish the program with 20-25 mg of Nolvadex or 100 mg of Clomid for an additional two weeks.

References

1 Vermeulen A., Comhaire F., Hormonal effects of an anti-estrogen, tamoxifen, in normal and oligospermic men, Fertil. Ster. 29 (1978) 320-27

2 Bruning PF, Bronfer JMG, Hart AAM, Jong-Bakker M, tamoxifen, serum lipoproteins and cardiovascular risk, Br. J. Cancer 1988 Oct, 58 (4) 497-9

liftsiron@steroidology

 

Do góry


Czym są sterydy


Before reading the following chapters it is vital the reader has a basic understanding of natural testosterone production and its actions. I realize that it is probably pretty boring for many readers but I have also found it is quite necessary foundational knowledge. Besides the obvious, it is kind of fun to find out what else "the boys" can do anyway. I wish to warn any sensitive readers about my writing style: Though some may take offense at my candidness concerning any topic including sexuality (yes, I said the "S" word) I apologize to no one who chooses to read beyond this point Simply stated, it is my right to freedom of expression and your right to choose not to read on or agree. (Yes, I once received a letter declaring me "perverse" for the words... "the boys became raisins no sun could shrink worse".)

There are several sex hormones. Some such as estradiol, estrone, and progesterone are sex hormones referred to as estrogens. Androstenedione, androstenediol, and testosterone are referred to as naturally occurring endogenous (made inside the body) androgens. The former group is the prominent hormones in females responsible for the formation of female pattern fat deposits such as in breast, hips, and buttock areas as well as the formation and maturation of the female sex organs. The latter group. Androgens, are the prominent hormones in males that are responsible for characteristics such as a deeper voice, increased muscle and bone mass, facial hair, increased body hair, male sex organ formation and development, and aggressiveness.

Both men and vwmen produce androgens and estrogens. Women's dominant production is estrogens, and men's dominant production is androgens. Reverse this and each will take on their counter-parts characteristic to quite some extent Our main focus for the following chapters is the male androgen testosterone and its almost endless

On average, men produce 4-10 mg of testosterone daily. This means that an average male can synthesize 28-70mg of endogenous testosterone weekly. However, before we go on, a basic understanding of other hormones is necessary also.Before reading the following chapters it is vital the reader has a basic understanding of natural testosterone production and its actions. I realize that it is probably pretty boring for many readers but I have also found it is quite necessary foundational knowledge. Besides the obvious, it is kind of fun to find out what else "the boys" can do anyway. I wish to warn any sensitive readers about my writing style: Though some may take offense at my candidness concerning any topic including sexuality (yes, I said the "S" word) I apologize to no one who chooses to read beyond this point Simply stated, it is my right to freedom of expression and your right to choose not to read on or agree. (Yes, I once received a letter declaring me "perverse" for the words... "the boys became raisins no sun could shrink worse".)

There are several sex hormones. Some such as estradiol, estrone, and progesterone are sex hormones referred to as estrogens. Androstenedione, androstenediol, and testosterone are referred to as naturally occurring endogenous (made inside the body) androgens. The former group is the prominent hormones in females responsible for the formation of female pattern fat deposits such as in breast, hips, and buttock areas as well as the formation and maturation of the female sex organs. The latter group. Androgens, are the prominent hormones in males that are responsible for characteristics such as a deeper voice, increased muscle and bone mass, facial hair, increased body hair, male sex organ formation and development, and aggressiveness.

Both men and vwmen produce androgens and estrogens. Women's dominant production is estrogens, and men's dominant production is androgens. Reverse this and each will take on their counter-parts characteristic to quite some extent Our main focus for the following chapters is the male androgen testosterone and its almost endless

On average, men produce 4-10 mg of testosterone daily. This means that an average male can synthesize 28-70mg of endogenous testosterone weekly. However, before we go on, a basic understanding of other hormones is necessary also.

Fragment pochodzi z książki L.Rea

 

Do góry

Copyright (c) 2003-2007 www.research.ovh.org. All rights reserved powerlifter.